Recent publications published by researchers at the MRC WIMM.
Unconventional MAIT cell responses to bacterial infections.
Journal article
Salio M., (2022), Semin Immunol, 61-64
The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation
Journal article
Kulicke CA. et al, (2021), Journal of Biological Chemistry, 101542 - 101542
CD1-MR1 EMBO workshop: Beyond MHC-restricted lymphocytes, Oxford September 2019.
Journal article
Klenerman P. et al, (2021), Mol Immunol, 134, 170 - 171
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.
Journal article
Crump NT. et al, (2021), Cell Rep, 35
Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection.
Journal article
Frost JN. et al, (2021), Med (N Y), 2, 164 - 179.e12
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
Journal article
Louka E. et al, (2021), J Exp Med, 218
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
Working paper
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)
Understanding and modulating the MR1 metabolite antigen presentation pathway
Journal article
SALIO M. and McWilliam HEG., (2020), Molecular Immunology
Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity.
Journal article
Pinto-Fernandez A. et al, (2020), Br J Cancer
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Journal article
Peng Y. et al, (2020), Nat Immunol, 21, 1336 - 1345
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.
Journal article
Preciado-Llanes L. et al, (2020), Proc Natl Acad Sci U S A, 117, 20717 - 20728
USP18 modulates the ISGylome, immune signaling and sensitizes tumor cells to irradiation and CTL recognition
Conference paper
Pinto-Fernandez A. et al, (2020), CANCER RESEARCH, 80
The immune modulating properties of Mucosal-Associated 1 Invariant T cells
Journal article
SALIO M. et al, (2020), Frontiers in Immunology
Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.
Journal article
Peng Y. et al, (2020), bioRxiv
Ligand-dependent downregulation of MR1 cell surface expression.
Journal article
Salio M. et al, (2020), Proc Natl Acad Sci U S A, 117, 10465 - 10475
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.
Journal article
Chen Y-L. et al, (2020), J Exp Med, 217
The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes.
Journal article
Lange J. et al, (2020), ACS Chem Biol, 15, 437 - 445
Interactions Between MAIT Cells and Dendritic Cells.
Journal article
Salio M. and Cerundolo V., (2020), Methods Mol Biol, 2098, 125 - 139
Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors.
Journal article
Lee CH. et al, (2020), Front Immunol, 11
Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.
Journal article
Bedard M. et al, (2019), Proc Natl Acad Sci U S A, 116, 23671 - 23681