Recent publications published by researchers at the MRC WIMM.
Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis
Tram TTB. et al, (2025)
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming.
Provine NM. et al, (2024), Eur J Immunol
Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression.
Nassiri I. et al, (2024), Bioinform Adv, 4
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
GARNER LC. et al, (2023), Nature Immunology
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.
Hackstein C-P. et al, (2022), Nat Commun, 13
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Hackstein C-P. et al, (2022)
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
Human MAIT cells show clonal diversity but transcriptional and functional homogeneity
Garner LC. et al, (2022)
An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Peng Y. et al, (2022), Nat Immunol, 23, 50 - 61
Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
Provine NM. et al, (2021), Eur J Immunol
MAIT cell activation augments adenovirus vector vaccine immunogenicity.
Provine NM. et al, (2021), Science, 371, 521 - 526
Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets.
FitzPatrick MEB. et al, (2021), Cell Rep, 34
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)