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Publications

Recent publications published by researchers at the MRC WIMM.

The immunology of multiple sclerosis.

Attfield KE. et al, (2022), Nat Rev Immunol

Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis.

Kaufmann M. et al, (2021), Med (N Y), 2, 296 - 312.e8

Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient.

Wurm H. et al, (2020), Mult Scler, 26, 1261 - 1264

A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.

Faergeman SL. et al, (2020), Cell Death Dis, 11

Structural and regulatory diversity shape HLA-C protein expression levels.

Kaur G. et al, (2017), Nat Commun, 8

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

Dendrou CA. et al, (2016), Sci Transl Med, 8

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.

Rühl G. et al, (2016), Neurol Neuroimmunol Neuroinflamm, 3

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Moutsianas L. et al, (2015), Nat Genet, 47, 1107 - 1113

CD8⁺ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis.

Willing A. et al, (2014), Eur J Immunol, 44, 3119 - 3128

TCR transgenic mice that shed light on immune and environmental regulators in multiple sclerosis.

Attfield KE. and Fugger L., (2013), J Immunol, 190, 3015 - 3017

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Gregory AP. et al, (2012), Nature, 488, 508 - 511

Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis.

Attfield KE. et al, (2012), Immunol Rev, 248, 10 - 22

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

Vergo S. et al, (2011), Brain, 134, 571 - 584

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model

Vergo S. et al, (2011), Brain, 134, 571 - 584

The role of antigenic modulation in controlling the efficacy of anti-CD20 monoclonal antibodies

Beers SA. et al, (2008), IMMUNOLOGY, 125, 48 - 49

Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation.

Beers SA. et al, (2008), Blood, 112, 4170 - 4177

Invariant NKT cells promote CD8+ cytotoxic T cell responses by inducing CD70 expression on dendritic cells.

Taraban VY. et al, (2008), J Immunol, 180, 4615 - 4620

Include forthcoming?