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Publications

Recent publications published by researchers at the MRC WIMM.

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.

Đukić N. et al, (2023), Sci Adv, 9

The Z-nucleic acid sensor ZBP1 in health and disease.

Maelfait J. and Rehwinkel J., (2023), J Exp Med, 220

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.

Moll T. et al, (2023), Life Sci Alliance, 6

Single-cell analysis of signalling and transcriptional responses to type I interferons

Rigby R. et al, (2023)

A simple transwell-based infection system for obtaining pure populations of VZV-infected cells.

Hertzog J. and Rehwinkel J., (2022), J Virol Methods

Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.

Peng R. et al, (2022), EMBO Rep

Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.

Hertzog J. et al, (2022), EMBO J, 41

Fractional response analysis reveals logarithmic cytokine responses in cellular populations

Nienałtowski K. et al, (2021), Nature Communications, 12

Interferon induction held captive in tumor cells.

Bridgeman A. and Rehwinkel J., (2021), Mol Cell, 81, 4109 - 4110

Publisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.

Clapes T. et al, (2021), Nat Cell Biol

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.

Tang Q. et al, (2021), Immunity, 54, 1961 - 1975.e5

Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.

Chauveau L. et al, (2021), EMBO Rep, 22

The RNA sensor MDA5 detects SARS-CoV-2 infection.

Sampaio NG. et al, (2021), Sci Rep, 11

TYPE I INTERFERON PATHWAY ASSAYS IN PATIENTS WITH RHEUMATIC AND MUSCULOSKELETAL DISEASES - SYSTEMATIC LITERATURE REVIEW (SLR) AND DEVELOPMENT OF CONSENSUS TERMINOLOGY FROM A EULAR TASKFORCE

Burska A. et al, (2021), ANNALS OF THE RHEUMATIC DISEASES, 80, 415 - 415

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype.

Fraser E. et al, (2021), Front Immunol, 12

The RNA sensor MDA5 detects SARS-CoV-2 infection

Sampaio N. et al, (2021)

Recognition of Z-RNA by ADAR1 limits interferon responses

Tang Q. et al, (2020)

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing.

Uggenti C. et al, (2020), Nat Genet, 52, 1364 - 1372

Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types.

Miar A. et al, (2020), Cancer Res, 80, 5245 - 5256

Regulation and inhibition of the DNA sensor cGAS.

Hertzog J. and Rehwinkel J., (2020), EMBO Rep

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