Recent publications published by researchers at the MRC WIMM.
CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade
Milotay G. et al, (2025), Nature Medicine
Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study.
Hamilton F. et al, (2024), Lancet Microbe
Relation between the Dantu blood group variant and bacteraemia in Kenyan children: a population-based case control study.
Kariuki SN. et al, (2024), J Infect Dis
Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes.
Gilchrist JJ. et al, (2024), Cell Genom, 4
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy.
Chong AY. et al, (2024), Am J Hum Genet, 111, 295 - 308
Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture
Schurz H. et al, (2024), eLife, 13
Intracranial Empyema in Children: A Single-center Retrospective Case Series.
Gilchrist JJ. et al, (2023), Pediatr Infect Dis J
Characterisation of the genetic determinants of context specific DNA methylation in primary monocytes
Gilchrist J. et al, (2023)
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma.
Taylor CA. et al, (2022), Nat Med, 28, 2592 - 2600
BIRC6 modifies risk of invasive bacterial infection in Kenyan children.
Gilchrist J. et al, (2022), Elife, 11
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.
Gilchrist JJ. et al, (2022), Nat Commun, 13
ACTR1Ahas pleiotropic effects on risk of leprosy, inflammatory bowel disease and atopy
Gilchrist J. et al, (2022)
Genetic variation at IL7 provides mechanistic insights into toxicity to immune checkpoint blockade
Fairfax B. et al, (2022)