Recent publications published by researchers at the MRC WIMM.
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.
Journal article
Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Journal article
Luis TC. et al, (2023), Nat Commun, 14
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Conference paper
Luis TC. et al, (2023), Nature communications, 14
Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells
Journal article
NERLOV C. et al, (2023), Blood
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.
Journal article
Wojtowicz EE. et al, (2023), Genome Biol, 24
Epigenetic programming defines haematopoietic stem cell fate restriction.
Journal article
Meng Y. et al, (2023), Nat Cell Biol, 25, 812 - 822
Slow integrin-dependent migration organizes networks of tissue-resident mast cells.
Journal article
Kaltenbach L. et al, (2023), Nat Immunol, 24, 915 - 924
Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging
Preprint
Jakobsen NA. et al, (2023)
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.
Journal article
Kaeppler JR. et al, (2022), EMBO Rep, 23
Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
Journal article
Braun TP. et al, (2022), Nat Commun, 13
DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
Journal article
Czeh M. et al, (2022), J Immunol, 208, 358 - 370
3016 – CCR1 AS A POTENTIAL THERAPEUTIC TARGET FOR AML IN THE ELDERLY
Journal article
Ren X. et al, (2022), Experimental Hematology, 111, S52 - S52
HAEMATOPOIESIS IS AN ORGANIZED PROCESS OF GRADUAL LOSS OF LINEAGE POTENTIALS
Conference paper
Drissen R. and Nerlov C., (2022), EXPERIMENTAL HEMATOLOGY, 111, S82 - S82
To bi or not to bi: Acute erythroid leukemias and hematopoietic lineage choice.
Journal article
Di Genua C. and Nerlov C., (2021), Exp Hematol, 97, 6 - 13
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing.
Journal article
Valletta S. et al, (2020), Nat Commun, 11
Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression.
Journal article
Mello T. et al, (2020), Int J Cancer, 146, 3410 - 3422
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Journal article
Di Genua C. et al, (2020), Cancer Cell, 37, 690 - 704.e8
CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions.
Journal article
Rabe JL. et al, (2020), Exp Hematol, 81, 1 - 15.e6
Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.
Journal article
Hua P. et al, (2019), Blood, 134, 2111 - 2115
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.
Journal article
Lopez CK. et al, (2019), Cancer Discov, 9, 1736 - 1753