Recent publications published by researchers at the MRC WIMM.
Author Correction: Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells.
Toghani D. et al, (2025), Nat Aging
Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells.
Toghani D. et al, (2025), Nat Aging
Epigenetic regulation of hematopoietic stem cell fate.
Meng Y. and Nerlov C., (2024), Trends Cell Biol
Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved.
Aksöz M. et al, (2024), Sci Immunol, 9
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.
Jakobsen NA. et al, (2024), Cell Stem Cell, 31, 1127 - 1144.e17
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis.
Gaertner F. et al, (2024), Nature
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells.
Carrelha J. et al, (2024), Nat Immunol, 25, 1007 - 1019
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.
Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC. et al, (2023), Nat Commun, 14
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC. et al, (2023), Nature communications, 14
Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells
NERLOV C. et al, (2023), Blood
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.
Wojtowicz EE. et al, (2023), Genome Biol, 24
Epigenetic programming defines haematopoietic stem cell fate restriction.
Meng Y. et al, (2023), Nat Cell Biol, 25, 812 - 822
Slow integrin-dependent migration organizes networks of tissue-resident mast cells.
Kaltenbach L. et al, (2023), Nat Immunol, 24, 915 - 924
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.
Kaeppler JR. et al, (2022), EMBO Rep, 23
Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
Braun TP. et al, (2022), Nat Commun, 13
DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
Czeh M. et al, (2022), J Immunol, 208, 358 - 370
3016 – CCR1 AS A POTENTIAL THERAPEUTIC TARGET FOR AML IN THE ELDERLY
Ren X. et al, (2022), Experimental Hematology, 111, S52 - S52
HAEMATOPOIESIS IS AN ORGANIZED PROCESS OF GRADUAL LOSS OF LINEAGE POTENTIALS
Drissen R. and Nerlov C., (2022), EXPERIMENTAL HEMATOLOGY, 111, S82 - S82