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Publications

Recent publications published by researchers at the MRC WIMM.

Epigenetic regulation of hematopoietic stem cell fate.

Meng Y. and Nerlov C., (2024), Trends Cell Biol

Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved.

Aksöz M. et al, (2024), Sci Immunol, 9

Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis.

Gaertner F. et al, (2024), Nature

Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells.

Carrelha J. et al, (2024), Nat Immunol

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.

Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nat Commun, 14

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nature communications, 14

Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells

NERLOV C. et al, (2023), Blood

Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.

Wojtowicz EE. et al, (2023), Genome Biol, 24

Epigenetic programming defines haematopoietic stem cell fate restriction.

Meng Y. et al, (2023), Nat Cell Biol, 25, 812 - 822

Slow integrin-dependent migration organizes networks of tissue-resident mast cells.

Kaltenbach L. et al, (2023), Nat Immunol, 24, 915 - 924

Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

Jakobsen NA. et al, (2023)

Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.

Kaeppler JR. et al, (2022), EMBO Rep, 23

Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.

Braun TP. et al, (2022), Nat Commun, 13

DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.

Czeh M. et al, (2022), J Immunol, 208, 358 - 370

3016 – CCR1 AS A POTENTIAL THERAPEUTIC TARGET FOR AML IN THE ELDERLY

Ren X. et al, (2022), Experimental Hematology, 111, S52 - S52

HAEMATOPOIESIS IS AN ORGANIZED PROCESS OF GRADUAL LOSS OF LINEAGE POTENTIALS

Drissen R. and Nerlov C., (2022), EXPERIMENTAL HEMATOLOGY, 111, S82 - S82

To bi or not to bi: Acute erythroid leukemias and hematopoietic lineage choice.

Di Genua C. and Nerlov C., (2021), Exp Hematol, 97, 6 - 13

Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing.

Valletta S. et al, (2020), Nat Commun, 11

Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression.

Mello T. et al, (2020), Int J Cancer, 146, 3410 - 3422

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