Recent publications published by researchers at the MRC WIMM.
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Journal article
Dingler FA. et al, (2020), Mol Cell, 80, 996 - 1012.e9
CDK activity provides temporal and quantitative cues for organizing genome duplication
Journal article
Perrot A. et al, (2018), PLOS Genetics, 14, e1007214 - e1007214
Bypass of Mutagenic O6-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases
Journal article
Räz MH. et al, (2016), Chemical Research in Toxicology, 29, 1493 - 1503
Touching base with arginine: recognition of O6-alkyl guanines by alkyltransferase-like protein Atl1
Conference paper
Wilkinson O. et al, (2014), Collection Symposium Series
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations
Journal article
Zhang F. et al, (2013), Nucleic Acids Research, 41, 5524 - 5532
The nitrosated bile acid DNA lesion O6 -carboxymethylguanine is a substrate for the human DNA repair protein O6 -methylguanine-DNA methyltransferase
Journal article
Senthong P. et al, (2013), Nucleic Acids Research, 41, 3047 - 3055
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation- interactions
Journal article
Wilkinson OJ. et al, (2012), Proceedings of the National Academy of Sciences, 109, 18755 - 18760
Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-Alkylguanines
Journal article
Latypov VF. et al, (2012), Molecular Cell, 47, 50 - 60
Flipping of alkylated DNA damage bridges base and nucleotide excision repair
Journal article
Tubbs JL. et al, (2009), Nature, 459, 808 - 813