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Publications

Recent publications published by researchers at the MRC WIMM.

Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis

Theorell J. et al, (2024), Proceedings of the National Academy of Sciences, 121

Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour microenvironments

Sivakumar S. et al, (2023)

Clinical, neurophysiological and serological clues for the diagnosis of neuromyotonia and distinction from cramp-fasciculation syndrome.

Spagni G. et al, (2023), Neuromuscul Disord

Abstract 668: The translational biology of small molecule GPR65 inhibitors: shared effects between mouse models and human primary tumors highlight the unique transformative potential of targeting a genetically validated innate immune checkpoint

Cipriani B. et al, (2023), Cancer Research, 83, 668 - 668

Continued expansion of long-lived effect CD8+T cells associates with durable response post-PD-1 blockade

Watson RA. et al, (2023), ANNALS OF ONCOLOGY, 34, S192 - S192

Deep sequencing of the T cell Receptor reveals common and reproducible CD8+signatures of response to checkpoint immunotherapy

Watson R. et al, (2023)

The lymphocyte stability index (LSI) forms a pan-cancer peripheral biomarker for overall survival post initiation of immune checkpoint blockade (ICB)

Watson RA. et al, (2023), ANNALS OF ONCOLOGY, 34, S235 - S235

Ibex: Variational autoencoder for single-cell BCR sequencing

Borcherding N. et al, (2022)

Efficacy and safety of rituximab in myelin oligodendrocyte glycoprotein antibody-associated disorders compared with neuromyelitis optica spectrum disorder: a systematic review and meta-analysis.

Spagni G. et al, (2022), J Neurol Neurosurg Psychiatry

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.

Kotanidis CP. et al, (2022), Lancet Digit Health, 4, e705 - e716

Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.

Damato V. et al, (2022), Proc Natl Acad Sci U S A, 119

Dissecting the autoantibody repertoire in CASPR2-antibody encephalitis

Sun B. et al, (2022), Journal of Neurology, Neurosurgery & Psychiatry, 93, A4.1 - A4

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58

An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.

Peng Y. et al, (2022), Nat Immunol, 23, 50 - 61

Double-jeopardy: scRNA-seq doublet/multiplet detection using multi-omic profiling.

Sun B. et al, (2021), Cell Rep Methods, 1

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)

Double-Jeopardy: scRNA-seq Doublet/Multiplet Detection Using Multi-Omic Profiling

Sun B. et al, (2020), SSRN Electronic Journal

The B cell immunobiology that underlies CNS autoantibody-mediated diseases.

Sun B. et al, (2020), Nat Rev Neurol, 16, 481 - 492

Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms.

Ramberger M. et al, (2020), Brain, 143, 1731 - 1745

Immunological mechanisms for the efficacy of Rituximab in aquaporin-4 autoantibody mediated Neuromyelitis Optica spectrum disorders

Damato V. et al, (2020), EUROPEAN JOURNAL OF NEUROLOGY, 27, 74 - 74

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