Recent publications published by researchers at the MRC WIMM.
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Journal article
Wang M. et al, (2023), Mol Cell, 83, 2417 - 2433.e7
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Journal article
Dingler FA. et al, (2020), Mol Cell, 80, 996 - 1012.e9
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms.
Journal article
Hodskinson MR. et al, (2020), Nature, 579, 603 - 608
TRAIP is a master regulator of DNA interstrand crosslink repair.
Journal article
Wu RA. et al, (2019), Nature, 567, 267 - 272
Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2-/- Hematopoietic Stem and Progenitor Cells.
Journal article
Yoon YM. et al, (2016), Stem Cell Reports, 7, 840 - 853
Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.
Journal article
Huan J. et al, (2015), Leukemia, 29, 2285 - 2295
Maternal high-fat diet and obesity compromise fetal hematopoiesis.
Journal article
Kamimae-Lanning AN. et al, (2015), Molecular metabolism, 4, 25 - 38
Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.
Journal article
Kamimae-Lanning AN. et al, (2013), Blood, 121, 2008 - 2012
L-Leucine alleviates Diamond-Blackfan anemia.
Journal article
Kamimae-Lanning AN. and Kurre P., (2012), Blood, 120, 2157 - 2158