Recent publications published by researchers at the MRC WIMM.
Backtracking to the future: unraveling the origins of childhood leukemia.
de Smith AJ. et al, (2024), Leukemia, 38, 416 - 419
Aberrant stem cell and developmental programs in pediatric leukemia.
Ling RE. et al, (2024), Front Cell Dev Biol, 12
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT. et al, (2023), Nat Commun, 14
Direct correction of haemoglobin E β-thalassaemia using base editors.
Badat M. et al, (2023), Nat Commun, 14
Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO. et al, (2023), Cancer Discov, 13, 364 - 385
A SINGLE-CELL PROTEIN-TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
Londono MQ. et al, (2023), EXPERIMENTAL HEMATOLOGY, 124, S129 - S129
DEVELOPMENTAL ORIGINS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
Roy A., (2023), EXPERIMENTAL HEMATOLOGY, 124, S26 - S26
Investigating the roles of fetal-specific genes in hematopoiesis
Welsh A. et al, (2023), JOURNAL OF IMMUNOLOGY, 210
PROM1/CD133 expression identifies highly proliferative MLL-AF4+blasts and correlates with a stem-like gene signature
Cross J. et al, (2023), KLINISCHE PADIATRIE, 235, 193 - 193
CD34+CD19-CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies.
Bueno C. et al, (2022), Blood, 140, 38 - 44
In utero origin of myelofibrosis presenting in adult monozygotic twins.
Sousos N. et al, (2022), Nat Med, 28, 1207 - 1211
Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome.
Li S. et al, (2022), Blood Adv
A PROTEIN - TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
Londono MQ. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S127 - S127
CD34+CD19-CD22+B- CELL PROGENITORS MIGHT UNDERLIE PHENOTYPIC ESCAPE IN PATIENTS TREATED WITH CD19-DIRECTED THERAPIES
Menendez P. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S112 - S112