Recent publications published by researchers at the MRC WIMM.
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Journal article
Lee CH. et al, (2023), Genome Med, 15
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Journal article
Matute JD. et al, (2023), J Exp Med, 220
Pathogenesis of fistulating Crohn's disease: a review.
Journal article
Chantelle McGregor CG. et al, (2022), Cell Mol Gastroenterol Hepatol
Lymphatic endothelia stakeout cryptic stem cells.
Journal article
Antanaviciute A. et al, (2022), Cell Stem Cell, 29, 1292 - 1293
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Journal article
Sazonovs A. et al, (2022), Nat Genet
Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.
Journal article
Serra EG. et al, (2022), Nat Commun, 13
Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.
Journal article
Buckley PR. et al, (2022), Brief Bioinform
HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses.
Journal article
Buckley PR. et al, (2022), Immunology
Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion.
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Aulicino A. et al, (2022), Commun Biol, 5
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Journal article
Rana N. et al, (2022), Cell
Isolation of human fetal intestinal cells for single-cell RNA sequencing.
Journal article
Fawkner-Corbett D. et al, (2021), STAR Protoc, 2
Interferon-Gamma-Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis.
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Sasson SC. et al, (2021), Gastroenterology, 161, 1229 - 1244.e9
A Pilot Study on Automatic Three-Dimensional Quantification of Barrett's Esophagus for Risk Stratification and Therapy Monitoring.
Journal article
Ali S. et al, (2021), Gastroenterology, 161, 865 - 878.e8
HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses
Journal article
Buckley PR. et al, (2021)
A sub-national real-time epidemiological and vaccination database for the COVID-19 pandemic in Canada.
Journal article
Berry I. et al, (2021), Sci Data, 8
Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.
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Koppens MAJ. et al, (2021), Gastroenterology, 161, 239 - 254.e9
IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.
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Hardman CS. et al, (2021), Sci Immunol, 6
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool.
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Curtius K. et al, (2021), Gut
Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn's disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease bioresource.
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Stournaras E. et al, (2021), Gut, 70, 677 - 686
Spatiotemporal analysis of human intestinal development at single-cell resolution.
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Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23