Recent publications published by researchers at the MRC WIMM.
Human Enteric Glia Diversity in Health and Disease: New Avenues for the Treatment of Hirschsprung Disease.
Windster JD. et al, (2024), Gastroenterology
Goblet cell differentiation subgroups in colorectal cancer.
Abdullayeva G. et al, (2024), Proc Natl Acad Sci U S A, 121
Biologic Therapy for Inflammatory Bowel Disease: Real-World Comparative Effectiveness and Impact of Drug Sequencing in 13 222 Patients within the UK IBD BioResource.
Kapizioni C. et al, (2024), J Crohns Colitis, 18, 790 - 800
Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study.
Chanchlani N. et al, (2024), Lancet Gastroenterol Hepatol, 9, 521 - 538
Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients.
Bai BYH. et al, (2024), J Crohns Colitis, 18, 431 - 445
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N. et al, (2024), Cell, 187, 1011 - 1015
HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis.
Baumdick ME. et al, (2023), Gastroenterology, 165, 946 - 962.e13
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Lee CH. et al, (2023), Genome Med, 15
A Roadmap for the Human Gut Cell Atlas.
Zilbauer M. et al, (2023), Nat Rev Gastroenterol Hepatol, 20, 597 - 614
Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn's Disease.
Hanić M. et al, (2023), Biomolecules, 13
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Matute JD. et al, (2023), J Exp Med, 220
A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses.
Buckley PR. et al, (2023), Immunother Adv, 3
Pathogenesis of fistulating Crohn's disease: a review.
Chantelle McGregor CG. et al, (2022), Cell Mol Gastroenterol Hepatol
Lymphatic endothelia stakeout cryptic stem cells.
Antanaviciute A. et al, (2022), Cell Stem Cell, 29, 1292 - 1293
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Sazonovs A. et al, (2022), Nat Genet
Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.
Serra EG. et al, (2022), Nat Commun, 13
Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.
Buckley PR. et al, (2022), Brief Bioinform, 23
HLA-dependent variation in SARS-CoV-2 CD8 + T cell cross-reactivity with human coronaviruses.
Buckley PR. et al, (2022), Immunology, 166, 78 - 103
Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion.
Aulicino A. et al, (2022), Commun Biol, 5