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Publications

Recent publications published by researchers at the MRC WIMM.

BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration

LEEDHAM S. et al, (2021), Gastroenterology

Spatiotemporal analysis of human intestinal development at single-cell resolution.

Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23

The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.

Baquero-Perez B. et al, (2019), Elife, 8

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.

Harnack C. et al, (2019), Nat Commun, 10

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Parikh K. et al, (2019), Nature, 567, 49 - 55

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.

Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17

TNF-alpha Regulates Plasmacytoid Dendritic Cells By Suppressing IFN-alpha Production and Enhancing Th1 and Th17 Cell Differentiation

Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70

Type I IFN Production Is Induced By Non-Haematopoietic Tissue Cells but Not Plasmacytoid Dendritic Cells in Preclinical Autoimmunity and SLE

Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70

TNF-A REGULATES PLASMACYTOID DENDRITIC CELLS BY SUPPRESSING IFN-A PRODUCTION AND ENHANCING TH1 AND TH17 CELL DIFFERENTIATION

Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 877 - 877

TYPE I INTERFERON IS PRODUCED BY NON-HAEMATOPOIETIC TISSUE RESIDENT CELLS BUT NOT PDCS IN PRE-CLINICAL AUTOIMMUNITY AND SLE

Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 139 - 140

Characterization and Genomic Localization of a SMAD4 Processed Pseudogene.

Watson CM. et al, (2017), J Mol Diagn, 19, 933 - 940

m6aViewer: software for the detection, analysis, and visualization of N6-methyladenosine peaks from m6A-seq/ME-RIP sequencing data.

Antanaviciute A. et al, (2017), RNA, 23, 1493 - 1501

Amelogenesis Imperfecta; Genes, Proteins, and Pathways.

Smith CEL. et al, (2017), Front Physiol, 8

Deficiency of the myogenic factor MyoD causes a perinatally lethal fetal akinesia.

Watson CM. et al, (2016), J Med Genet, 53, 264 - 269

OPTIMISATION OF THE THP-1 CELL MODEL SYSTEM FOR INTERROGATION OF DIFFERENTIAL MACROPHAGE POLARISATION IN HUMAN DISEASE

Graham AE. et al, (2016), ANNALS OF THE RHEUMATIC DISEASES, 75, A49 - A49

Enhanced diagnostic yield in Meckel-Gruber and Joubert syndrome through exome sequencing supplemented with split-read mapping.

Watson CM. et al, (2016), BMC Med Genet, 17

A Chromosome 7 Pericentric Inversion Defined at Single-Nucleotide Resolution Using Diagnostic Whole Genome Sequencing in a Patient with Hand-Foot-Genital Syndrome.

Watson CM. et al, (2016), PLoS One, 11

OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization.

Antanaviciute A. et al, (2015), Bioinformatics, 31, 3822 - 3829

GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles.

Antanaviciute A. et al, (2015), Bioinformatics, 31, 2728 - 2735

Include forthcoming?