Recent publications published by researchers at the MRC WIMM.
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Journal article
Weeratunga P. et al, (2023), Nat Commun, 14
Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.
Journal article
Koppens MAJ. et al, (2021), Gastroenterology, 161, 239 - 254.e9
Spatiotemporal analysis of human intestinal development at single-cell resolution.
Journal article
Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.
Journal article
Baquero-Perez B. et al, (2019), Elife, 8
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Journal article
Harnack C. et al, (2019), Nat Commun, 10
Colonic epithelial cell diversity in health and inflammatory bowel disease.
Journal article
Parikh K. et al, (2019), Nature, 567, 49 - 55
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
Journal article
Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
TNF-A REGULATES PLASMACYTOID DENDRITIC CELLS BY SUPPRESSING IFN-A PRODUCTION AND ENHANCING TH1 AND TH17 CELL DIFFERENTIATION
Conference paper
Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 877 - 877
TNF-alpha Regulates Plasmacytoid Dendritic Cells By Suppressing IFN-alpha Production and Enhancing Th1 and Th17 Cell Differentiation
Conference paper
Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70
Type I IFN Production Is Induced By Non-Haematopoietic Tissue Cells but Not Plasmacytoid Dendritic Cells in Preclinical Autoimmunity and SLE
Conference paper
Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70
TYPE I INTERFERON IS PRODUCED BY NON-HAEMATOPOIETIC TISSUE RESIDENT CELLS BUT NOT PDCS IN PRE-CLINICAL AUTOIMMUNITY AND SLE
Conference paper
Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 139 - 140
Characterization and Genomic Localization of a SMAD4 Processed Pseudogene.
Journal article
Watson CM. et al, (2017), J Mol Diagn, 19, 933 - 940
m6aViewer: software for the detection, analysis, and visualization of N6-methyladenosine peaks from m6A-seq/ME-RIP sequencing data.
Journal article
Antanaviciute A. et al, (2017), RNA, 23, 1493 - 1501
Amelogenesis Imperfecta; Genes, Proteins, and Pathways.
Journal article
Smith CEL. et al, (2017), Front Physiol, 8
Deficiency of the myogenic factor MyoD causes a perinatally lethal fetal akinesia.
Journal article
Watson CM. et al, (2016), J Med Genet, 53, 264 - 269
Enhanced diagnostic yield in Meckel-Gruber and Joubert syndrome through exome sequencing supplemented with split-read mapping.
Journal article
Watson CM. et al, (2016), BMC Med Genet, 17
A Chromosome 7 Pericentric Inversion Defined at Single-Nucleotide Resolution Using Diagnostic Whole Genome Sequencing in a Patient with Hand-Foot-Genital Syndrome.
Journal article
Watson CM. et al, (2016), PLoS One, 11
OPTIMISATION OF THE THP-1 CELL MODEL SYSTEM FOR INTERROGATION OF DIFFERENTIAL MACROPHAGE POLARISATION IN HUMAN DISEASE
Conference paper
Graham AE. et al, (2016), ANNALS OF THE RHEUMATIC DISEASES, 75, A49 - A49
OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization.
Journal article
Antanaviciute A. et al, (2015), Bioinformatics, 31, 3822 - 3829
GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles.
Journal article
Antanaviciute A. et al, (2015), Bioinformatics, 31, 2728 - 2735