Recent publications published by researchers at the MRC WIMM.
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Weeratunga P. et al, (2023), Nat Commun, 14
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N. et al, (2022), Cell, 185, 283 - 298.e17
Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.
Koppens MAJ. et al, (2021), Gastroenterology, 161, 239 - 254.e9
Spatiotemporal analysis of human intestinal development at single-cell resolution.
Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.
Baquero-Perez B. et al, (2019), Elife, 8
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack C. et al, (2019), Nat Commun, 10
Colonic epithelial cell diversity in health and inflammatory bowel disease.
Parikh K. et al, (2019), Nature, 567, 49 - 55
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
TNF-A REGULATES PLASMACYTOID DENDRITIC CELLS BY SUPPRESSING IFN-A PRODUCTION AND ENHANCING TH1 AND TH17 CELL DIFFERENTIATION
Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 877 - 877
TNF-alpha Regulates Plasmacytoid Dendritic Cells By Suppressing IFN-alpha Production and Enhancing Th1 and Th17 Cell Differentiation
Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70
Type I IFN Production Is Induced By Non-Haematopoietic Tissue Cells but Not Plasmacytoid Dendritic Cells in Preclinical Autoimmunity and SLE
Psarras A. et al, (2018), ARTHRITIS & RHEUMATOLOGY, 70
TYPE I INTERFERON IS PRODUCED BY NON-HAEMATOPOIETIC TISSUE RESIDENT CELLS BUT NOT PDCS IN PRE-CLINICAL AUTOIMMUNITY AND SLE
Psarras A. et al, (2018), ANNALS OF THE RHEUMATIC DISEASES, 77, 139 - 140
Characterization and Genomic Localization of a SMAD4 Processed Pseudogene.
Watson CM. et al, (2017), J Mol Diagn, 19, 933 - 940
m6aViewer: software for the detection, analysis, and visualization of N6-methyladenosine peaks from m6A-seq/ME-RIP sequencing data.
Antanaviciute A. et al, (2017), RNA, 23, 1493 - 1501
Deficiency of the myogenic factor MyoD causes a perinatally lethal fetal akinesia.
Watson CM. et al, (2016), J Med Genet, 53, 264 - 269
Enhanced diagnostic yield in Meckel-Gruber and Joubert syndrome through exome sequencing supplemented with split-read mapping.
Watson CM. et al, (2016), BMC Med Genet, 17
OPTIMISATION OF THE THP-1 CELL MODEL SYSTEM FOR INTERROGATION OF DIFFERENTIAL MACROPHAGE POLARISATION IN HUMAN DISEASE
Graham AE. et al, (2016), ANNALS OF THE RHEUMATIC DISEASES, 75, A49 - A49
OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization.
Antanaviciute A. et al, (2015), Bioinformatics, 31, 3822 - 3829