Recent publications published by researchers at the MRC WIMM.
Immune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease.
FitzPatrick MEB. et al, (2025), Nat Immunol
Human Enteric Glia Diversity in Health and Disease: New Avenues for the Treatment of Hirschsprung Disease.
Windster JD. et al, (2024), Gastroenterology
CELLeBT: exploring physical B cell-T cell clonal interactions through single-cell multi-omics
Bashford-Rogers R. et al, (2024)
Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
Heterozygous COL17A1 variants are a frequent cause of amelogenesis imperfecta.
Hany U. et al, (2024), J Med Genet, 61, 347 - 355
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N. et al, (2024), Cell, 187, 1011 - 1015
SPATIALLY RESOLVED INSIGHTS INTO FISTULATING CROHN'S DISEASE PATHOGENESIS: UNVEILING MOLECULAR HETEROGENEITY
McGregor C. et al, (2024), GASTROENTEROLOGY, 166, S47 - S47
Spatially resolved insights into fistulating Crohn's disease pathogenesis: Unveiling molecular heterogeneity
Mcgregor C. et al, (2024), JOURNAL OF CROHNS & COLITIS, 18, I372 - I372
Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis
Weeratunga P. et al, (2024)
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Weeratunga P. et al, (2023), Nat Commun, 14
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Lee CH. et al, (2023), Genome Med, 15
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Matute JD. et al, (2023), J Exp Med, 220
A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses.
Buckley PR. et al, (2023), Immunother Adv, 3
Lymphatic endothelia stakeout cryptic stem cells.
Antanaviciute A. et al, (2022), Cell Stem Cell, 29, 1292 - 1293
Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.
Buckley PR. et al, (2022), Brief Bioinform, 23
HLA-dependent variation in SARS-CoV-2 CD8 + T cell cross-reactivity with human coronaviruses.
Buckley PR. et al, (2022), Immunology, 166, 78 - 103
Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion.
Aulicino A. et al, (2022), Commun Biol, 5
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Rana N. et al, (2022), Cell, 185, 283 - 298.e17
Isolation of human fetal intestinal cells for single-cell RNA sequencing.
Fawkner-Corbett D. et al, (2021), STAR Protoc, 2