Recent publications published by researchers at the MRC WIMM.
The bone marrow is the primary site of thrombopoiesis.
Journal article
Asquith NL. et al, (2023), Blood
Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis.
Journal article
Akbulut AC. et al, (2023), Thromb Haemost, 123, 808 - 839
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Journal article
Barrachina MN. et al, (2023), Nature Cardiovascular Research, 2, 746 - 763
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Journal article
Barrachina MN. et al, (2023), bioRxiv
Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Journal article
Khan AO. et al, (2023), Cancer Discov, 13, 364 - 385
Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues.
Journal article
Reyat JS. et al, (2023), Front Cardiovasc Med, 10
Rare missense variants in Tropomyosin-4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding.
Journal article
Stapley RJ. et al, (2022), J Thromb Haemost, 20, 478 - 485
Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms
Conference paper
Li R. et al, (2022), BLOOD, 140, 1091 - 1092
Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients
Conference paper
Khan A. et al, (2022), BLOOD, 140, 1679 - 1681