Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.

Reckzeh K.; Kizilkaya H.; Helbo AS.; Alrich ME.; Deslauriers AG.; Grover A.; Rapin N.; Asmar F.; Grønbæk K.; Porse B.; Borregaard N.; Vestweber D.; Nerlov C.; Theilgaard-Mönch K.

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Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.

Reckzeh K., Kizilkaya H., Helbo AS., Alrich ME., Deslauriers AG., Grover A., Rapin N., Asmar F., Grønbæk K., Porse B., Borregaard N., Vestweber D., Nerlov C., Theilgaard-Mönch K.

EMCN is a novel marker of human HSCs. EMCN is a more specific marker of HSCs than CD34 as it can discriminate HSCs from lineage-committed HPCs.

Original publication

DOI

10.1182/bloodadvances.2018015743

Type

Journal article

Journal

Blood Adv

Publication Date

10/07/2018

Volume

Pages

1628 - 1632

Keywords

Adult, Adult Stem Cells, Gene Expression Regulation, Hematopoietic Stem Cells, Humans, Sialoglycoproteins