A novel rearrangement of the human beta-like globin gene cluster.
Trent RJ., Bowden DK., Old JM., Wainscoat JS., Clegg JB., Weatherall DJ.
The first example of a duplication involving the human beta-like globin genes has been characterised in DNA from a native of Vanuatu. Restriction endonuclease mapping has shown that a 5 kb insert of DNA in the gamma-delta-beta gene cluster is due to duplication of the Ggamma-globin gene and results in a new rearrangement 5'-epsilon-Ggamma-Ggamma-Agamma-delta-beta-3'.