Colleges
Jack Tan
DPhil, BSc (Hons)
RDM Principal Investigator
Dr Tan is a Principal Investigator at the MRC Translational Immune Discovery Unit.
His research focuses developing next-generation protein nanoparticle-based vaccines and antibody therapeutics against infectious diseases. He is particularly interested in understanding how the architecture of protein nanoparticle vaccines influences their immunogenicity, as well as investigating mucosal vaccine immunity to improve vaccine design against respiratory pathogens such as coronavirus.
Dr Tan is part of an international consortium (Oxford-Caltech-CPI-Ingenza) funded by the Coalition of Epidemics Preparedness Innovations (CEPI) to develop novel a pan-sarbecovirus (SARS-like betacoronavirus) nanoparticle vaccine. He is also a Career Development Fellow at the Chinese-Academy of Medical Sciences-Oxford Institute, and a Fellow by Special Election at St Edmund Hall.
Key publications
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Journal article
Tan TK. et al, (2021), Nat Commun, 12
Recent publications
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Journal article
Sadler HL. et al, (2025), J Virol
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Huhn A. et al, (2025), Nat Commun, 16
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Cheow P-S. et al, (2024), Avian Pathol, 1 - 9
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Hills RA. et al, (2024), Nat Nanotechnol
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Journal article
Zheng MZM. et al, (2023), Sci Adv, 9
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Preprint
Huhn A. et al, (2023)
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Journal article
Gelinas AD. et al, (2023), Mol Ther Nucleic Acids, 31, 370 - 382
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Hills RA. et al, (2023), bioRxiv
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Huang K-YA. et al, (2023), Nat Commun, 14
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Kandasamy M. et al, (2023), Elife, 12
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Preprint
Jeewandara C. et al, (2023)
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Journal article
Zheng MZM. et al, (2022), J Immunol, 209, 1832 - 1836
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Zheng MZM. et al, (2022), J Immunol
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Cohen AA. et al, (2022), Science, 377
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Buchanan CJ. et al, (2022), Science, 377
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Vester SK. et al, (2022), Nat Commun, 13
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Journal article
Jeewandara C. et al, (2022), Immunology
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Jayathilaka D. et al, (2022), Clin Exp Immunol, 208, 323 - 331
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Jeewandara C. et al, (2022), Immun Inflamm Dis, 10
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MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8