DPhil, BSc (Hons)
I am a EPA Cephalosporin Early Research and Teaching Fellow at St Edmund Hall. I am currently working as a postdoctoral scientist in Alain Townsend lab at the Weatherall Institute of Molecular Medicine on developing a single cycle influenza vaccine (S-FLU) for clinical trials. Apart form that, I am trying to further understand the immune responses against influenza elicited by S-FLU in animal models and humans. We have also recently started developing vaccines and therapeutic antibodies for coronavirus (SARS-nCoV-2).
Broadly inhibiting anti-neuraminidase monoclonal antibodies induced by trivalent influenza vaccine and H7N9 infection in humans.
Rijal P. et al, (2019), J Virol
Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases
De Caneva A. et al, (2018), HUMAN GENE THERAPY, 29, A115 - A115
Lung-targeted lentiviral vector mediates passive immunisation against influenza
Tan TK. et al, (2018), HUMAN GENE THERAPY, 29, A119 - A119
Use of Pseudotyped, Replication-Deficient Influenza to Facilitate Testing of Gene Delivery Strategies for Treatment of Highly Infectious Diseases
Tan TK. et al, (2018), MOLECULAR THERAPY, 26, 242 - 243
Development of Recombinant Adeno-Associated Viral Vector (rAAV) for Passive Immunisation Against Ebola
Tan TK. et al, (2017), MOLECULAR THERAPY, 25, 182 - 182