Contact information
Research groups
Melinda Czéh-Bhardwaj
PhD
CRUK Clinical Scientist
I am a CRUK Clinical Scientist in Professor Claus Nerlov's group at the MRC Molecular Haematology Unit at the Weatherall Institute of Molecular Medicine (WIMM).
I received my PhD from the Free University of Berlin, Germany, in 2008 in the field of Tumor Immunology. After my PhD, I trained in General Paediatrics and Paediatric Haematology and Oncology at the Children's Hospital of Charité, Berlin and at UKM, Münster, Germany, from 2007 to 2017. I am currently working as a Clinical Fellow in Paediatric haematology at the Royal Marsden Hospital and in Community Paediatrics at the John Radcliffe Hospital.
Parallel to my clinical training, I worked as a Clinical/Postdoctoral Fellow with Professor Frank Rosenbauer from 2014 to 2017 at the Institute of Molecular Tumor Biology, Münster. I was investigating the role of epigenetic mechanisms during haematopoietic differentiation and participated in the characterisation of a mouse model with biphenotypic leukaemia and transdifferentiation mechanisms.
I moved to Oxford in November 2017 after I was awarded a CRUK Clinical Scientist Fellowship to join the group of Professor Claus Nerlov. My research activity focuses on the role of haematopoietic lineage bias during ontogeny and in the development of different types of acute leukaemias, particularly in the characterisation of MLL-induced leukaemias.
Recent publications
-
DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
Czeh M. et al, (2022), J Immunol, 208, 358 - 370
-
Uncovering a new cellular origin for acute myeloid leukemia with lineage plasticity.
Czeh M. and Rosenbauer F., (2017), Mol Cell Oncol, 4
-
Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke P. et al, (2016), EMBO J, 35, 2399 - 2416
-
Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo J. et al, (2011), Eur J Immunol, 41, 3187 - 3197
-
Congenital tumors of the central nervous system
Czeh M. and Kaindl AM., (2011), Brain Cancer, Tumor Targeting and Cervical Cancer, 217 - 230