Mary Thompson
Computational Biology Researcher / Trainer
- Trainer for the OBDS training programme
- Postdoctoral computational biologist
I train biologists how to process and interpret their genomics data as part of the Oxford Biomedical Data Science training programme. My research focuses on transcriptional regulation during brain development, with a view to better understanding the effect of genetic variants in neurological disorders.
Biography
I obtained my undergraduate degree in biochemistry and cell biology at Rice University, USA. I pursued my PhD at the Massachusetts Institute of Technology, USA, where I worked with Wendy Gilbert on my thesis exploring the functions of specific ribosomal proteins in translational control. I then did a postdoc in the lab of Ilan Davis at the University of Oxford, UK, where I studied the regulation of RNA metabolism during fruit fly brain development and in synaptic plasticity. Throughout my PhD and postdoc, my research combined experimental work with computation, and I developed a passion for genomics data analysis and reproducible research. I have also worked as a bioinformatician in the private sector where I helped support R&D efforts by analyzing genomics data. In my current position, I am helping to train new computational biologists as part of the Oxford Biomedical Data Science Training Programme. My research is focused on regulation driven by non-coding regions of the genome during brain development using single-cell genomics data.
Recent publications
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Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences.
Journal article
Lee JY. et al, (2022), Elife, 11