Contact information
Research groups
Mariana Pereira Pinho
Postdoctoral Researcher
Tumor-specific T cell response
My research focuses on the analysis of T cells capable of recognizing and reacting to tumor antigens. Specifically, we are interested in evaluating the specificity and function of tumor-reactive CD8 T cells in breast cancer patients.
Key publications
-
Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response.
Journal article
Pinho MP. et al, (2019), Oncoimmunology, 8
-
Dendritic cell membrane CD83 enhances immune responses by boosting intracellular calcium release in T lymphocytes.
Journal article
Pinho MP. et al, (2014), J Leukoc Biol, 95, 755 - 762
-
Dendritic-tumor cell hybrids induce tumor-specific immune responses more effectively than the simple mixture of dendritic and tumor cells.
Journal article
Pinho MP. et al, (2016), Cytotherapy, 18, 570 - 580
Recent publications
-
Adjuvant Vaccination with Allogenic Dendritic Cells Significantly Prolongs Overall Survival in High-Grade Gliomas: Results of a Phase II Trial
Journal article
Lepski G. et al, (2023), Cancers, 15, 1239 - 1239
-
Near-Complete Remission of Glioblastoma in a Patient Treated with an Allogenic Dendritic Cell-Based Vaccine: The Role of Tumor-Specific CD4+T-Cell Cytokine Secretion Pattern in Predicting Response and Recurrence
Journal article
Pinho MP. et al, (2022), International Journal of Molecular Sciences, 23, 5396 - 5396
-
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
Journal article
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
-
HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses.
Journal article
Buckley PR. et al, (2022), Immunology
-
HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses
Journal article
Buckley PR. et al, (2021)