Websites
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Department of Oncology
Department
Kaima Tsukada
PhD
Postdoctoral Researcher
- JSPS Postdoctoral Research Fellow
Biography
Kaima Tsukada is a postdoctoral researcher at the Blackford Group in the Department of Oncology, based at the MRC Weatherall Institute of Molecular Medicine. He is also a Japan Society for Promotion of Sciences (JSPS) postdoctoral research fellow.
He studied mechanical engineering at the National Institute of Technology in Japan for his BEng until 2016. During his MEng and PhD, he studied nuclear engineering and radiation biology under the supervision of Prof Yoshihisa Matsumoto at the School of Environment and Society in the Tokyo Institute of Technology in Japan. After obtaining his PhD, he joined the Blackford Group as a postdoctoral researcher in June 2021. He was awarded Research Fellowships from the Japan Society for Promotion of Sciences between 2020-2022 and 2022-2024.
Key publications
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BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
Tsukada K. et al, (2024), Mol Cell, 84, 640 - 658.e10
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The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks.
Shorrocks A-MK. et al, (2021), Nat Commun, 12
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The FHA domain of PNKP is essential for its recruitment to DNA damage sites and maintenance of genome stability
Tsukada K. et al, (2021), Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis
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Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase
Tsukada K. et al, (2021), PLoS One
Recent publications
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BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
Tsukada K. et al, (2024), Mol Cell, 84, 640 - 658.e10
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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.
Hodson C. et al, (2022), Proc Natl Acad Sci U S A, 119
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Diminished or inversed dose-rate effect on clonogenic ability in Ku-deficient rodent cells
Tsuchiya H. et al, (2021), Journal of Radiation Research
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Functional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity
Asa AD. et al, (2021), Journal of Radiation Research
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Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase
Tsukada K. et al, (2021), PLoS One