Direct line (MRC Weatherall Institure of Molecular Medicine) 01865 222316
Emeritus Professor of Paediatric Haematology
- MRC Investigator, MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine
I have a longstanding interest in understanding the developmentally-regulated, molecular and biological properties of fetal haematopoietic stem and progenitor cells (HSPC) that underlie the development of blood problems that affect babies and young children.
Irene Roberts qualified in medicine at Glasgow University, Scotland in 1978. After training in paediatrics and haematology and doctoral training in Garret FitzGerald's lab, Vanderbilt University, Nashville, she joined Lucio Luzzatto's lab at Imperial College London where she established her own group. She moved to the Department of Paediatrics and MRC Molecular Haematology Unit in the Weatherall Institute of Molecular Medicine, University of Oxford, in 2013.
I am an Associate Editor of Blood and Vice-chair of the Scientific Committee on Blood Disorders in Childhood of the American Society for Hematology. I am also a member of the European Hematology Association Global Outreach Committee and formerly held senior positions in the Executive Board and a number of other constituted and ad hoc committees. I was previously an Honorary Consultant Paediatric Haematologist at Oxford University Hospitals NHS Trust and Imperial College Healthcare NHS Trust and Theme Lead for the Non-Malignant Haematological Disorders for the National Institute of Health Research (NIHR) Translational Research Collaboration Rare Diseases Collaboration.
GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.
Roberts I. et al, (2013), Blood, 122, 3908 - 3917
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.
Roy A. et al, (2012), Proc Natl Acad Sci U S A, 109, 17579 - 17584