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Alastair Smith

Postdoctoral Researcher

I joined the Milne lab in 2018 after completing my PhD in the lab of Joan Boyes at the University of Leeds in 2018, where I investigated the temporal regulation of V(D)J recombination. My current research investigates the emergence of novel enhancers in leukaemia, with a focus on MLL-AF4 Acute Lymphoblastic Leukaemia (ALL).

I use a wide variety of high-throughput techniques (ChIP-seq, low cell number ChIPMentation, ATAC-seq, RNA-seq and Capture-C ) together with machine learning and other bioinformatic methods to better understand the regulation of chromatin and gene expression.