Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Many congratulations to Christopher Booth (Mead/Jacobsen group) and Marieke Oudelaar (Hughes/Higgs group), who won this year’s Radcliffe Department of Medicine Graduate Prize.


Chris Booth completed his DPhil under the supervision of Adam Mead and Sten Eirik Jacobsen. Chris led a study that provided experimental evidence that the phenotypic and gene expression profiles of a cancer can be traced back to those of the cell of origin. For the first time since the identification of human early thymic progenitor (ETP) leukemia, Chris confirmed that ETPs do indeed possess the potential to become LSCs upon introduction of recurrent ETP leukemia associated mutations. Chris published his findings in a first author article in Cancer Cell and has given oral presentations of his work at two international meetings. Find out more his work

 

 

Marieke Oudelaar completed her DPhil under the supervision of Doug Higgs and Jim Hughes. Her research describing chromosomal interactions within single cells has made a major contribution to recent developments in the application of Chromosome Conformation Capture techniques. Although this won’t have an immediate clinical application, it will, in time have a very large impact on the field. Marieke’s research is published in Nature Genetics. Find out more about her work. 

 

Find out more about the prize on the RDM website.

Similar stories

September is Childhood Cancer Awareness Month

September is Childhood Cancer Awareness Month, where our Childhood Leukaemia research group have taken action to help raise awareness for this cause.

Anjali Kusumbe receives the RMS Life Sciences Medal

The Royal Microscopical Society awards celebrate the best in microscopy, recognising those making a special contribution to microscopy, cytometry and imaging.

Wellcome Trust funding success for Jim Hughes and James Davies

£3.6 million in funding awarded by the Wellcome Trust to combine cutting-edge 3D genome technologies with machine learning approaches to decipher the role of the non-coding genome in disease.

Study of T-cell receptor activation leads to surprising discovery

A study from Davis Group is the first to describe the structure of the T-cell receptor when bound to an activating ligand. The findings shed light on an important trigger in the immune system, and suggest a completely new process by which cell receptors can be activated.

Biotech spinout MiroBio acquired by Gilead Sciences for ~£332m

Co-founded by Prof. Simon Davis, MiroBio focuses on developing therapeutics for inflammatory diseases.