New study discovers genetic changes linked to leukaemia in children with Down’s syndrome
Researchers at the MRC MHU have discovered the specific gene mutations that are required for the development of leukaemia in children with Down’s syndrome.
Read moreTwo weeks of inspiring science
For the second year running, the MRC WIMM hosted a group of work experience students from under-represented backgrounds, in partnership with in2scienceUK.
Read moreMachine learning meets microscopy - Subjectivity dethroned
How can we remove subjectivity from science, whilst keeping the human in the loop?
Read moreCRISPR-Cas9 – what’s left to know?
Dominic Owens, PhD student in the De Bruijn group at MRC MHU, recounts how puzzling results and a fortuitous lab meeting uncovered unexpected outcomes of CRISPR editing and changed the direction of his research.
Read moreMRC Human Immunology Unit
Human immunology and the development of treatments against infectious diseases, cancer, allergy and autoimmune disease.
MRC Molecular Haematology Unit
Understanding how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.
Centre for Computational Biology
Using computational biology to help understand complex biological systems and combat a range of human diseases.
Latest Publications
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The impact of chemo- and radiotherapy treatments on selfish de novo FGFR2 mutations in sperm of cancer survivors.
Maher GJ. et al, (2019), Hum Reprod
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Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K. et al, (2019), J Biol Chem
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DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.
Godfrey L. et al, (2019), Nat Commun, 10
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Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses.
Abd Hamid M. et al, (2019), Cancer Immunol Res
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KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.
Bery N. et al, (2019), Nat Commun, 10
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Two weeks of inspiring science
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MRC WIMM wins VC Public Engagement Award
10 July 2019