Rosalie Rietjens
Postdoctoral Researcher
I joined the Mead Group as a postdoctoral researcher in 2026 after completing my PhD at Leiden University in the Netherlands. During my PhD, I investigated the cellular and molecular mechanisms underlying kidney injury and repair, with a particular focus on spatial metabolomics and spatial transcriptomics. My work contributed to the development and application of spatial multi-omics approaches to better understand the complex tissue microenvironment following acute kidney injury.
My current research focuses on understanding how the bone marrow microenvironment regulates normal and malignant haematopoiesis. I use single cell and spatial technologies to investigate how stem cells interact with their surrounding niche, and how these interactions are altered during disease development. By integrating high-resolution technologies with functional studies, I aim to uncover mechanisms that could inform new therapeutic strategies for haematological malignancies.
More broadly, I am interested in developing and applying spatial multi-omics technologies to answer biologically and clinically relevant questions, bridging methodological innovation with translational research.
Recent publications
Spatial metabolomics reveals persistent localized niche-specific metabolic failure in kidneys following ischemia-reperfusion injury
Preprint
Rietjens RGJ. et al, (2025)
Fasting mimicking diet in diabetic mice partially preserves glomerular endothelial glycocalyx coverage, without changing the diabetic metabolic environment
Journal article
van der Velden AIM. et al, (2024), American Journal of Physiology-Renal Physiology, 326, F681 - F693
Unveiling the role of Mfsd2a and LPC-DHA in kidney repair
Journal article
Rietjens RGJ. and Rabelink TJ., (2023), Journal of Lipid Research, 64, 100422 - 100422
Phosphatidylinositol metabolism of the renal proximal tubule S3 segment is disturbed in response to diabetes
Journal article
Rietjens RGJ. et al, (2023), Scientific Reports, 13