Home — MRC Weatherall Institute of Molecular Medicine

Illustration showing the structures of receptors on the surface of γδ T-cells, B cells and αβ T-cells.

Structure of a key “trigger” of the immune response solved

An international collaboration, involving researchers from the laboratories of Professor Rossjohn at Monash University (Australia), and Professor Simon Davis at the MRC Translational Immune Discovery Unit, has led to a breakthrough in our understanding of how immune responses are started.

Senior Fellowship awarded to Beth Psaila

Congratulations to Beth Psaila, who has been awarded a Senior Fellowship funded by Cancer Research UK in partnership with Rosetrees Trust.

Illustration of blood cell production in the bone marrow.

Of Mice and Men - Researchers demonstrate evolutionary conservation of blood stem cell subtypes

Researchers from the MRC MHU have shown that blood stem cell subtypes found in mice also exist in humans. This provides important information for research into therapies to alleviate the negative effects of ageing.

MRC WIMM Researchers at IF Oxford - book now

IF Oxford returns as a digital and in-real-life science and ideas Festival with events running throughout October 2024.

Conceptual illustration of targeted cell therapy.

Yellowstone Biosciences spinout launches to advance cutting-edge cancer therapies

Yellowstone Biosciences, a biotechnology spinout, has launched to pioneer new cancer treatments using advanced T-cell therapies based on groundbreaking research from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford.

Linking Fundamental Research to Clinical Innovation

Leading research with the aim of improving human health.

Discover. Translate. Advance.

The MRC WIMM's core mission is to improve human health through the pursuit of fundamental research, the development of new technology, and the translation of discoveries to the clinic.

MRC WIMM Research Areas

Research at the MRC WIMM spans 5 core areas.

MRC Translational Immune Discovery Unit

Pioneering the future in the study of human immunity to uncover the molecular pathways driving immune-mediated diseases.

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MRC Molecular Haematology Unit

Understanding how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.

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Centre for Computational Biology

Using computational biology to help understand complex biological systems and combat a range of human diseases.

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Latest publications

Risk Stratification in Older Intensively Treated Patients With AML.
Journal article

Versluis J. et al, (2024), J Clin Oncol
Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved.
Journal article

Aksöz M. et al, (2024), Sci Immunol, 9
Introduction to a review series on globin disorders.
Journal article

Coates TD. and Roberts I., (2024), Blood, 144, 797 - 798
Quantum mechanical electronic and geometric parameters for DNA k-mers as features for machine learning.
Journal article

Masuda K. et al, (2024), Sci Data, 11
How Important Is Unrelated Donor Human Leukocyte Antigen Disparity in the Post-Transplant Cyclophosphamide Era?
Journal article

Chakraverty R., (2024), J Clin Oncol

More Publications

Upcoming Seminars

ADP-ribosylation in antiviral responses

Monday, 16 September 2024, 12pm to 1pm

Speakers: Dr Nicholas Hoch
Tracing the origin of pediatric leukemia using single-cell genome sequencing

Tuesday, 17 September 2024, 1pm to 2pm

Speakers: Dr Ruben van Boxtel
Understanding dysregulation of antibody and immune memory responses to chronic viral infection

Wednesday, 25 September 2024, 1.30pm to 2.30pm

Speakers: Professor Kim Good-Jacobson
CELL- BASED GENE THERAPIES FOR CANCER

Thursday, 26 September 2024, 12pm to 1pm

Speakers: James S. Economou, M.D., PhD., Beaumont Distinguished Professor
Peptide Specific Immune Receptors

Friday, 27 September 2024, 9.15am to 10.15am

Speakers: Dr Malcolm Sim
Title TBC

Friday, 11 October 2024, 9.15am to 10.15am

Speakers: Lambe Group

More seminars

MRC WIMM Interactive Timeline

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Structure of a key “trigger” of the immune response solved

MRC Translational Immune Discovery Unit

MRC Molecular Haematology Unit

Centre for Computational Biology

Latest publications

Upcoming Seminars

ADP-ribosylation in antiviral responses

Tracing the origin of pediatric leukemia using single-cell genome sequencing

Understanding dysregulation of antibody and immune memory responses to chronic viral infection

CELL- BASED GENE THERAPIES FOR CANCER

Peptide Specific Immune Receptors

Title TBC

MRC WIMM Interactive Timeline