MRC Molecular Haematology Unit
The MRC Molecular Haematology Unit (MHU) was founded in 1980 and is now located in the Weatherall Institute of Molecular Medicine. It includes fourteen research teams with over 100 scientists who share a common interest in understanding the process by which multipotential haemopoietic stem cells become committed and differentiate into the highly specialised cells found in the peripheral blood (red cells, granulocytes, lymphocytes and platelets). In addition we study how these processes are perturbed in acquired and inherited blood diseases (e.g. thalassaemia, myelodysplasia and leukaemia). Our work is closely integrated with the provision of NHS service (via the clinical Department of Haematology) to patients with blood diseases. Some permanent members of the MHU are active clinicians working in the University of Oxford Departments of Haematology and Clinical Genetics providing the Unit with access to clinical material and ensuring that our scientific developments are rapidly translated into improved clinical care.
The aim of the MRC MHU is to understand how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.
Ultimately our purpose is to improve the management of patients with inherited and acquired blood diseases.