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Sumana Sharma

Sir Henry Wellcome Postdoctoral Fellow

I am a Sir Henry Wellcome Postdoctoral fellow at the MRC Weatherall Institute of Molecular Medicine (WIMM). My general research interests are in understanding context-specific signalling in cells. My background is in characterising receptor interactions using genome-scale CRISPR/Cas9 screening approaches. More recently, I have also been using computational tools to characterise signalling from -omics datasets, specifically using large-scale vulnerability screens and protein-protein interaction networks. Currently, my research focuses on understanding immunomodulation by checkpoint inhibitory receptors on the surface of T-cells, for which I am using a range of CRISPR-based genome editing experimental and network-based computational approaches. 

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