R. Spencer Tong
By understanding normal tissue homeostasis, we can better elucidate the distinct processes that lead to malignancy. My interests lie in characterizing these clonal dynamics (inc. evolution) at a single-cell level and how they relate to aging, especially in the paternal germline.
I earned a BA from Washington University in St. Louis and trained with Prof. Todd Druley at the Washington University School of Medicine. While there, I helped develop tests that allowed for the detection of rare pre-leukemic and pre-relapse subclonal mutations.
I am reading for a PhD at the MRC Weatherall Institute of Molecular Medicine with the supervision of Profs. Anne Goriely & Andrew Wilkie.
I hold the Oxford-Sir David Weatherall Scholarship and am grateful to Green Templeton College & the MRC WIMM for this support.
Clonal hematopoiesis and risk of acute myeloid leukemia
Young AL. et al, (2019), Haematologica, 104, 2410 - 2417
Distal chromosome 16p11.2 duplications containing SH2B1 in patients with scoliosis
Sadler B. et al, (2019), Journal of Medical Genetics, 56, 427 - 433
Rare Event Detection Using Error-corrected DNA and RNA Sequencing
Wong WH. et al, (2018), Journal of Visualized Experiments