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Kate Attfield


Kate Attfield

Principal Investigator

Multiple sclerosis (MS) is the most common, chronic disabling neurological condition in young adults, afflicting more than 2.5 million people worldwide. Genome-wide association studies (GWAS) have identified more than 200 risk loci as contributing to disease susceptibility. However, the clinical utility of this data ultimately requires functional translation to identify cell types or pathways that are perturbed by these variants and to understand the role that exogenous triggers, which activate and drive the disease. Our research aims to unravel this complexity using an array of experimental platforms and to integrate and complement our findings with clinical data.