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Grace A. Meaker

DPhil Student

Grace Meaker undertook her Biological Sciences BSc at Cardiff University, with a specialism in Genetics. She gained experience with CRISPR in Dr Thomas Gorochowski’s lab at the University of Bristol, as well as working on fine-tuning genetic circuits.

Grace’s work in Oxford centres around haematopoietic stem cell biology In Dr Adam Wilkinson's group, using molecular biology techniques to discover key transcription factors controlling expansion of haematopoietic cells.

Publications

Meaker, G.A., Hair, E.J., Gorochowski, T.E. Advances in engineering CRISPR-Cas9 as a molecular Swiss Army knife. Synthetic Biology, Volume 5, Issue 1, 2020.
https://doi.org/10.1093/synbio/ysaa021

Bartoli, V., Meaker, G.A., di Bernardo, M. et al. Tunable genetic devices through simultaneous control of transcription and translation. Nature Communications, Volume 11, Issue 2095, 2020. https://doi.org/10.1038/s41467-020-15653-7

Khoo, H.M.*, Meaker G.A.*, Wilkinson A.C. Ex Vivo Expansion and Genetic Manipulation of Mouse Hematopoietic Stem Cells in Polyvinyl Alcohol-Based Cultures. Journal of Visualised Experiments, 2021.
https://doi.org/10.3791/64791-v

Meaker G.A., Wilkinson A.C. Ex vivo Hematopoietic Stem Cell Expansion Technologies: Recent Progress, Applications, and Open Questions. Experimental Hematology, 2023.
https://doi.org/10.1016/j.exphem.2023.12.001