Felix A Radtke
DPhil Student
My research experience includes studying neutrophil biology in homeostasis and inflammation in humans and mice and novel diagnostical methods for paediatric Lyme disease at Heidelberg University and the Brigham and Women’s Hospital, Harvard Medical School.
After graduating from medical school, I joined the Vyas lab to study haematopoiesis and haematological malignancies. During my time at Oxford, I am focusing my research on the mutational landscape of haematopoietic malignancies and identifying the transcriptomic and epigenetic landscape of patients with acute myeloid leukaemia treated with novel therapeutics. A particular interest is the transcriptomic state and the clonal architecture of TP53 mutations in AML.
By applying and improving novel sequencing technologies, the laboratory aims to understand the events leading to the development of acute myeloid leukaemia and to improve treatment opportunities.
I hold the Oxford – Sir David Weatherall Scholarship from Green Templeton College and am co-funded by the Radcliffe Department of Medicine/Weatherall Institute of Molecular Medicine (WIMM Prize Studentship). I am very grateful to the college and the institute for their support.
Recent publications
-
Journal article
Hackert NS. et al, (2023), Nat Commun, 14
-
Journal article
Turkalj S. et al, (2023), STAR Protoc, 4
-
Journal article
Turkalj S. et al, (2023), HemaSphere, 7
-
Journal article
Grieshaber-Bouyer R. et al, (2022), Annals of the rheumatic diseases, 81, 805 - 814
-
Journal article
Huang FY. et al, (2022), Blood advances, 6, 2081 - 2091