Christian Babbs
BSc (Hons) DPhil
Head of Genome Engineering
Generating genetically altered models for the research community
I lead the Geneome Engineering, Transgenics and Virus Production facility at the WIMM. We generate all reagents for genome engineering. We also modify embryonic stem cells and 1-cell embryos for rapid production of model systems.
Key publications
-
ATR-16 syndrome: mechanisms linking monosomy to phenotype.
Journal article
Babbs C. et al, (2020), J Med Genet, 57, 414 - 421
-
De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder.
Journal article
Babbs C. et al, (2014), J Med Genet, 51, 737 - 747
-
Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I.
Journal article
Babbs C. et al, (2013), Haematologica, 98, 1383 - 1387
-
Genetic dissection of the α-globin super-enhancer in vivo.
Journal article
Hay D. et al, (2016), Nat Genet, 48, 895 - 903
-
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.
Journal article
Taylor JC. et al, (2015), Nat Genet, 47, 717 - 726
Recent publications
-
Author Correction: The α-globin super-enhancer acts in an orientation-dependent manner.
Journal article
Kassouf MT. et al, (2025), Nat Commun, 16
-
The α-globin super-enhancer acts in an orientation-dependent manner.
Journal article
Kassouf MT. et al, (2025), Nat Commun, 16
-
Erythropoiesis in the human
Chapter
Higgs DR. et al, (2025), Hoffbrand S Postgraduate Haematology Eighth Edition, 43 - 55
-
Loss-of-Function Variants in SUPT5H as Modifying Factors in Beta-Thalassemia.
Journal article
Harteveld CL. et al, (2024), Int J Mol Sci, 25
-
Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future.
Journal article
Amid A. et al, (2024), Blood
ORCID
0000-0002- 1898-5878