Contact information

Christian Babbs

BSc (Hons) DPhil

Head of Genome Engineering

Generating genetically altered models for the research community

I lead the Geneome Engineering, Transgenics and Virus Production facility at the WIMM. We generate all reagents for genome engineering. We also modify embryonic stem cells and 1-cell embryos for rapid production of model systems.

Key publications

ATR-16 syndrome: mechanisms linking monosomy to phenotype.

Babbs C. et al, (2020), J Med Genet, 57, 414 - 421

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D. et al, (2016), Nat Genet, 48, 895 - 903

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Taylor JC. et al, (2015), Nat Genet, 47, 717 - 726

De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder.

Babbs C. et al, (2014), J Med Genet, 51, 737 - 747

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I.

Babbs C. et al, (2013), Haematologica, 98, 1383 - 1387

Recent publications

MAFF regulates ferroptotic sensitivity through iron homeostasis and fatty acid synthesis.

Vilaplana Lopera N. et al, (2026), Cell Death Dis

Using Patient Feedback to Improve Treatment Outcomes for Patients with Congenital Dyserythropoietic Anaemia Type I Receiving Interferon Therapy.

Frey K. et al, (2026), J Clin Med, 15

Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.

Preston AE. et al, (2025), Nat Commun, 16

Author Correction: The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

More publications

ORCID

0000-0002- 1898-5878

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Contact information

Christian Babbs

Key publications

Recent publications

ORCID