Computational Biologist and Genomic Datascience Trainer
Dynamics of Transcriptional Regulation
I am a computational and molecular biologist focused on understanding the molecular dynamics of transcriptional regulation in mammalian tissues in response to fluctuating developmental, hormonal and circadian stimuli.
CGAT-core: a python framework for building scalable, reproducible computational biology workflows
Cribbs AP. et al, (2019), F1000Research, 8, 377 - 377
Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo.
George CL. et al, (2017), Mol Cell Endocrinol, 439, 46 - 53
Glucocorticoids—timing, binding and environment
Lightman SL. and George CL., (2014), Nature Reviews Endocrinology, 10, 71 - 72
The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment
Conway-Campbell BL. et al, (2011), Molecular Endocrinology, 25, 944 - 954