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New collaborative research from MRC WIMM researchers and the Mommersteeg Group in the Department of Physiology, Anatomy & Genetics at the University of Oxford shows that a protein called Runx1 plays a significant role in the formation of the cardiac scar that forms after the heart is injured, a scar that is known to inhibit heart regeneration. In the zebrafish, a freshwater fish known to be able to fully regenerate its heart after damage, they show that the absence of Runx1 results in enhanced regeneration. This indicates a potential new therapeutic target for heart repair.
Tarun Gupta
DPhil (Oxon) MA (Cantab) BMBChir (Oxon) MRCP Tarun Gupta - NIHR Academic Clinical Lecturer Gastroenterology
