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New collaborative research from MRC WIMM researchers and the Mommersteeg Group in the Department of Physiology, Anatomy & Genetics at the University of Oxford shows that a protein called Runx1 plays a significant role in the formation of the cardiac scar that forms after the heart is injured, a scar that is known to inhibit heart regeneration. In the zebrafish, a freshwater fish known to be able to fully regenerate its heart after damage, they show that the absence of Runx1 results in enhanced regeneration. This indicates a potential new therapeutic target for heart repair.
David Jackson
Group Leaders MRC TIDU
B.A. (Natural Sciences), Ph.D. (Biochemistry) David Jackson - Professor of Human Immunology
Anindita Roy
Group Leaders MRC MHU
MRCPCH FRCPath PhD Anindita Roy - Professor of Paediatric Haematology
Alain Townsend
Group Leaders MRC TIDU
FRS FRCP Alain Townsend - Emeritus Professor of Molecular Immunology
Bethan Psaila
Group Leaders MRC MHU
MA; MBBS; MRCP; FRCPath; PhD Bethan Psaila - Associate Professor of Haematology
Jill Brown
MRC MHU Researchers
BSc (Hons), Postgraduate Certificate in Clinical Cytogenetics Jill Brown - Research Assistant