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Defining targets to cure the incurable

The discovery of an aberrantly expressed gene by a team of MRC WIMM researchers could lead to curative treatments for currently incurable childhood leukemias.

Study maps role CD8 T cells play in IBD

MRC HIU NDM

Researchers from the MRC-Human Immunology Unit, supported by the NIHR Oxford Biomedical Research Centre, have used an ‘atlas’ of immune cells in the human colon to find evidence of the role of CD8 T cells in inflammatory bowel disease. The findings could pave the way for more targeted treatments for this chronic disorder.

How studying anti-viral immune responses led to a discovery about cancer

MRC HIU

Researchers at the MRC Weatherall Institute of Molecular Medicine have recently discovered why a class of cancer drugs is beneficial only in a subset of patients. The results could pave the way for the future development of these drugs, known as PNP-inhibitors, as personalised medicines.

Genetic study reveals Polynesians and Native Americans made contact before European arrival

Analyses of samples from the MRC WIMM archives conducted by Stanford Medicine researchers and collaborators have settled a long-brewing controversy about whether ancient Polynesians and Native Americans had contact.

Uncovering immune responses in COVID-19 patients

COVID-19 MRC HIU NDM

A new study finds T cell immune response variation in recovered COVID-19 patients, including epitopes potentially important for vaccine design.

MRC WIMM researchers part of ground-breaking new study into long-term health impacts of coronavirus

COVID-19 MRC HIU NDM

A major UK research study into the long-term health impacts of COVID-19 on hospitalised patients has been launched.

Introducing CytoCensus: A new cell mapping tool

A machine learning tool to characterise complex 4D image tissue and organism data could aid research into diseases such as neurodegenerative disorders and cancer.

Serum iron may be useful biomarker to identify COVID-19 disease severity

A new study led by Radcliffe Department of Medicine researchers analyses iron levels in COVID-19 intensive care patients to find that patients with very low levels of iron had severe respiratory failure.

Oxford-Sri Lanka study to compare COVID-19 immune response

COVID-19 MRC HIU RDM

The study builds on a successful collaboration and will compare T cell and antibody responses to uncover the role of ‘background’ immunity to virus strains already in circulation, including infections with similar coronaviruses.

Chapman group joins the MRC WIMM

Associate Professor Ross Chapman joins us along with his research group from the 1st of June 2020.

New method to identify active mutations in cancer cells

The Ahmed lab and collaborators develop new sequencing approach to uncover active mutational processes in cancer and pre-cancer conditions.

Discovery of new ligands implicated in immune system function

New findings by a team of MRC WIMM researchers could help us harness immune system cells by enhancing antigen-specific responses.

Nerlov and Vyas labs develop first pre-clinical model of rare leukaemia

MRC MHU

The collaboration has led to the first pre-clinical model of acute erythroid leukaemia.

A MEGA study in blood cancer

The study, led by Dr Beth Psaila, identifies a new approach for targeting cancer-driven cells.

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