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Uncovering immune responses in COVID-19 patients

COVID-19 MRC HIU NDM

A new study finds T cell immune response variation in recovered COVID-19 patients, including epitopes potentially important for vaccine design.

MRC WIMM researchers part of ground-breaking new study into long-term health impacts of coronavirus

COVID-19 MRC HIU NDM

A major UK research study into the long-term health impacts of COVID-19 on hospitalised patients has been launched.

Introducing CytoCensus: A new cell mapping tool

A machine learning tool to characterise complex 4D image tissue and organism data could aid research into diseases such as neurodegenerative disorders and cancer.

Serum iron may be useful biomarker to identify COVID-19 disease severity

A new study led by Radcliffe Department of Medicine researchers analyses iron levels in COVID-19 intensive care patients to find that patients with very low levels of iron had severe respiratory failure.

Oxford-Sri Lanka study to compare COVID-19 immune response

COVID-19 MRC HIU RDM

The study builds on a successful collaboration and will compare T cell and antibody responses to uncover the role of ‘background’ immunity to virus strains already in circulation, including infections with similar coronaviruses.

Chapman group joins the MRC WIMM

Associate Professor Ross Chapman joins us along with his research group from the 1st of June 2020.

New method to identify active mutations in cancer cells

The Ahmed lab and collaborators develop new sequencing approach to uncover active mutational processes in cancer and pre-cancer conditions.

Discovery of new ligands implicated in immune system function

New findings by a team of MRC WIMM researchers could help us harness immune system cells by enhancing antigen-specific responses.

Nerlov and Vyas labs develop first pre-clinical model of rare leukaemia

MRC MHU

The collaboration has led to the first pre-clinical model of acute erythroid leukaemia.

A MEGA study in blood cancer

The study, led by Dr Beth Psaila, identifies a new approach for targeting cancer-driven cells.

Heart scarring run by Runx1 gene

MRC MHU RDM

New collaborative research from MRC WIMM researchers and the Mommersteeg Group in the Department of Physiology, Anatomy & Genetics at the University of Oxford shows that a protein called Runx1 plays a significant role in the formation of the cardiac scar that forms after the heart is injured, a scar that is known to inhibit heart regeneration. In the zebrafish, a freshwater fish known to be able to fully regenerate its heart after damage, they show that the absence of Runx1 results in enhanced regeneration. This indicates a potential new therapeutic target for heart repair.

Celebrating Professor Doug Higgs’ time as MRC WIMM Director

Our enormous thanks and gratitude to Doug for his many years of excellent and inspirational leadership.

Coronavirus immune research from MRC HIU on BBC Radio 4

MRC HIU NDM

Professor of Immunology Tao Dong from the MRC Human Immunology Unit (MRC HIU) appeared on BBC Radio 4’s The World This Weekend to discuss her group’s coronavirus research.

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