MRC Molecular Haematology Unit
We aim to understand how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders. Ultimately, our purpose is to improve the prognosis of patients with inherited and acquired blood diseases.
Developing a rapid and cost-effective way to identify newborns at risk of leukaemia
MRC WIMM researchers have developed a new method to quickly identify cancerous cells in babies at risk of leukaemia. The team hope that the new protocol could make rapid testing more accessible for clinical laboratories around the globe.
Read moreLatest Publications
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S. et al, (2019), Blood, 134, 1059 - 1071
ATR-16 syndrome: mechanisms linking monosomy to phenotype.
Babbs C. et al, (2020), J Med Genet, 57, 414 - 421
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus.
Oudelaar AM. et al, (2019), Nat Commun, 10
Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.
Hua P. et al, (2019), Blood, 134, 2111 - 2115
Stabilization of chromatin topology safeguards genome integrity.
Ochs F. et al, (2019), Nature, 574, 571 - 574