MRC Molecular Haematology Unit
We aim to understand how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders. Ultimately, our purpose is to improve the prognosis of patients with inherited and acquired blood diseases.
Nerlov and Vyas labs develop first pre-clinical model of rare leukaemia
The collaboration has led to the first pre-clinical model of acute erythroid leukaemia.
Read moreCoronavirus research in the MRC MHU
Researchers from the Medical Research Council Molecular Haematology Unit are working hard to understand coronavirus infection and help combat the COVID-19 pandemic. Here you can find out more about our research.
Read moreLatest Publications
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S. et al, (2019), Blood, 134, 1059 - 1071
ATR-16 syndrome: mechanisms linking monosomy to phenotype.
Babbs C. et al, (2020), J Med Genet, 57, 414 - 421
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus.
Oudelaar AM. et al, (2019), Nat Commun, 10
Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.
Hua P. et al, (2019), Blood, 134, 2111 - 2115
Stabilization of chromatin topology safeguards genome integrity.
Ochs F. et al, (2019), Nature, 574, 571 - 574
Latest News
Heart scarring run by Runx1 gene
27 April 2020