MRC Molecular Haematology Unit
We aim to understand how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders. Ultimately, our purpose is to improve the prognosis of patients with inherited and acquired blood diseases.
Unit Director
Study With Us
Applications are now open for our 4 year PhD Studentships. Deadline for applications is the 11th January 2019.
Read more£635,000 towards new Therapy Acceleration Laboratory
Deutsche Bank employees across the UK raised this generous sum via their ‘One Day’ initiative, in collaboration with Cure Leukaemia
Read moreInspiring the next generation of scientists
MRC WIMM hosts its first work experience programme for under-represented students
Read moreTri-C tells us which enhancers are in the loop
How do multiple enhancers control the activity of a single gene? A new paper from Marieke Oudelaar in the Hughes/Higgs labs presents a novel approach called “Tri-C”, which uncovers how cis-regulatory elements interact together in higher-order structures.
Read moreLatest Publications
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Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion.
Buono M. et al, (2018), Nat commun, 9
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Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.
Oudelaar AM. et al, (2018), Nat genet
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A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.
Brown JM. et al, (2018), Nat commun, 9
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Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.
Quevedo CE. et al, (2018), Nat commun, 9
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How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.
Truch J. et al, (2018), Methods mol biol, 1832, 105 - 130
Latest News
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MRC WIMM students win RDM graduate prize
3 December 2018
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£635,000 towards new Therapy Acceleration Laboratory
22 November 2018
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Applications invited for the role of Institute Director
6 November 2018
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"That’s fascinating!"
22 October 2018