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Davis Group: T-cell Biology

We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.

Bannard Group: B Cell Immunology

We study the cellular interactions and molecular events that lead to the development of high affinity and protective antibodies during humoral immune responses. Our main focus is the germinal centre reaction.

Cornall Group: B cell development and immune regulation

Our aims are to understand B cell development and diseases associated with abnormal antibody production. Inadequate or excessive immune responses lead to immunodeficiency or autoimmune and inflammatory diseases, which place a major economic and social burden on world health and the quality of human life. So, we are interested in the normal processes of immune function and how individuals vary due to inherited or acquired differences.

Dong Group: Human T cell responses against Viruses & Cancer

Our group focuses on determining the factors which affect T cells both in the control of viral infection and in the development of cancer.

Drakesmith Group: Iron and Immunity

We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.

Eggeling Group

We apply and optimize advanced optical microscopy techniques, such as super-resolution STED microscopy, to decipher molecular dynamics in an unprecedented way. Our main focus is molecular plasma membrane organization, especially following immune responses.

Ho Group: Translational Lung Immunology

We are interested in how immunological responses impact on mechanisms of lung injury and repair.

Jackson Group: Lymphatic Trafficking Research Group

We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.

Koohy Group: Machine Learning and Integrative Approaches in Immunology

We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.

Multi-dimensional Innate and Adaptive lmmune responses

We focus on gaining a better understanding of the mechanisms that control the cell-cell interplay required for optimal expansion and activation of tumour-specific T cell populations and to apply this knowledge to the development of better treatment strategies in cancer patients.

Newbold Group: Molecular Parasitology

Our group's interests centre on the role of multi-gene families in malaria in pathogenesis, immune evasion and their evolution.

Ogg Group: Cutaneous Immunology Group

The aim of the group is to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.

Oxford Centre for Neuroinflammation

We bring together biomedical, analytical and clinical expertise to shed new light on the causes that underpin neurodegenerative diseases.

Simmons Group: Intestinal Immunology Lab

We use state-of the-art molecular and computational approaches to understand mechanisms of intestinal immunity and how those go wrong in the inflammatory bowel diseases, Crohn’s disease and Ulcerative Colitis.