Search results
Found 10077 matches for
Wilkie Group: Clinical Genetics
The ability to sequence whole exomes and genomes of individual people has revolutionised our ability to explore the full spectrum of genetic mutations causing serious human diseases. Working closely with the craniofacial teams based in Oxford and other UK units, we specialise in the application of these methods to children born with a serious malformation of the skull termed craniosynostosis.
Davis Group: T-cell Biology
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Drakesmith Group: Iron and Immunity
We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.
Cornall Group: B cell development and immune regulation
Our aims are to understand B cell development and diseases associated with abnormal antibody production. Inadequate or excessive immune responses lead to immunodeficiency or autoimmune and inflammatory diseases, which place a major economic and social burden on world health and the quality of human life. So, we are interested in the normal processes of immune function and how individuals vary due to inherited or acquired differences.
McHugh Group: DNA Damage and Repair
Studying DNA damage and repair to understand the causes of cancer and improve its treatment.
Fairfax Group: Genomics of Inflammation and Cancer Immunology
Using genetic and epigenetic data to understand basic mechanisms of inflammation.