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Search results (16)

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MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemia.

Lau I-J. et al, (2026), Blood

FACT safeguards promoter topology by maintaining nucleosomes and restricting chromatin factor spreading

Dopico-Fernandez AM. et al, (2026)

Menin maintains enhancer-promoter interactions in a leukemia-specific manner

Sharlandjieva V. et al, (2026)

A genome-wide screen identifies Runx2 as a novel regulator of hematopoietic stem cell expansion and T-cell commitment.

Meaker GA. et al, (2025), Blood, 146, 3188 - 3200

Menin inhibitor DS-1594b drives differentiation and induces synergistic lethality in combination with venetoclax in acute myeloid leukemia cells with rearranged mixed-lineage leukemia and mutated nucleophosmin-1.

Ciaurro V. et al, (2025), Haematologica

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.

Smith AL. et al, (2025), Blood, 146, 2073 - 2087

TRANSCRIPTION ELONGATION AND ABERRANT ENHANCER ACTIVATION IN LEUKEMIA

Milne T. et al, (2025), EXPERIMENTAL HEMATOLOGY, 151

The fetal specific geneLIN28Bis essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia

Ling R. et al, (2024)

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression between patients

Smith A. et al, (2024)

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Smith AL. et al, (2024), BLOOD, 144, 201 - 202

The Fetal Specific Gene LIN288 Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Ling RE. et al, (2024), BLOOD, 144, 199 - 200

Endothelial sensing of AHR ligands regulates intestinal homeostasis.

Wiggins BG. et al, (2023), Nature, 621, 821 - 829

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.

Crump NT. et al, (2023), Nat Commun, 14

Endothelial sensing of AHR ligands regulates intestinal homeostasis

Wiggins BG. et al, (2023)

A High-Throughput Cell Culture Model of Idiopathic Pulmonary Fibrosis (IPF) for Gene Therapy Applications

Cerezuela MP. et al, (2022), MOLECULAR THERAPY, 30, 292 - 292

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