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Search results (205)

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Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency.

Leithner A. et al, (2025), Proc Natl Acad Sci U S A, 122

The Structural Biology of T-Cell Antigen Detection at Close Contacts.

Lui Y. et al, (2025), Immunol Rev, 331

Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.

Sun B. et al, (2025), Sci Adv, 11

Structure of a fully assembled γδ T cell antigen receptor.

Gully BS. et al, (2024), Nature, 634, 729 - 736

Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.

Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15

A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.

Sharma S. et al, (2024), Life Sci Alliance, 7

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10

Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade.

Pearce H. et al, (2023), Cancer Immunol Res, 11, 435 - 449

Antigen discrimination by T cells relies on size-constrained microvillar contact.

Jenkins E. et al, (2023), Nat Commun, 14

The kinase occupancy of T cell coreceptors reconsidered.

Mørch AM. et al, (2022), Proc Natl Acad Sci U S A, 119

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.

Kennedy A. et al, (2022), Nat Immunol, 23, 1365 - 1378

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.

Sušac L. et al, (2022), Cell, 185, 3201 - 3213.e19

Single-cell measurements of two-dimensional binding affinity across cell contacts.

Chouliara M. et al, (2021), Biophys J, 120, 5032 - 5040

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling.

Chen KY. et al, (2021), Proc Natl Acad Sci U S A, 118

HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities.

Yang H. et al, (2021), Sci Immunol, 6

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