Search results (207)
« Back to PublicationsRealizing the potential of agonistic antibody immunotherapy.
Cragg MS. et al, (2026), Nat Rev Drug Discov
PD-1 signaling and PD-1 blockade-mediated tumor control are established at microvillar T cell contacts.
Jenkins E. et al, (2026), Sci Immunol, 11
Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency.
Leithner A. et al, (2025), Proc Natl Acad Sci U S A, 122
The Structural Biology of T-Cell Antigen Detection at Close Contacts.
Lui Y. et al, (2025), Immunol Rev, 331
Structure of a fully assembled γδ T cell antigen receptor.
Gully BS. et al, (2024), Nature, 634, 729 - 736
Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.
Sharma S. et al, (2024), Life Sci Alliance, 7
Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10
Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade.
Pearce H. et al, (2023), Cancer Immunol Res, 11, 435 - 449
Antigen discrimination by T cells relies on size-constrained microvillar contact.
Jenkins E. et al, (2023), Nat Commun, 14
The kinase occupancy of T cell coreceptors reconsidered.
Mørch AM. et al, (2022), Proc Natl Acad Sci U S A, 119
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Kennedy A. et al, (2022), Nat Immunol, 23, 1365 - 1378
Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Sušac L. et al, (2022), Cell, 185, 3201 - 3213.e19
Single-cell measurements of two-dimensional binding affinity across cell contacts.
Chouliara M. et al, (2021), Biophys J, 120, 5032 - 5040