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Search results (45)

« Back to Publications

Enabling whole genome sequencing analysis from FFPE specimens in clinical oncology.

Domenico D. et al, (2025), Nat Commun, 16

Deconvoluting clonal and cellular architecture in IDH-mutant acute myeloid leukemia.

Sirenko M. et al, (2025), Cell Stem Cell, 32, 1102 - 1121.e5

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.

Brierley CK. et al, (2025), Nat Genet, 57, 1478 - 1492

Tumor-Infiltrating Clonal Hematopoiesis.

Pich O. et al, (2025), N Engl J Med, 392, 1594 - 1608

ENGINEERING CAR-T CELLS FOR EFFECTIVE THERAPY AMID JAK INHIBITION

Gannon I. et al, (2025), BONE MARROW TRANSPLANTATION, 60, 331 - 332

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.

Li R. et al, (2024), Sci Transl Med, 16

Development of a First-in-Class CAR-T Therapy Against Calreticulin-Mutant Neoplasms and Evaluation in the Relevant Human Tissue Environment

Rampotas A. et al, (2024), BLOOD, 144, 871 - 872

RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar Study

Brierley CK. et al, (2024), BLOOD, 144, 3146 - 3147

Implementing human bone marrow organoids to interrogate microenvironmental influences on the efficacy of blood cancer immunotherapies

Wong ZC. et al, (2024), CANCER RESEARCH, 84

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.

Brierley CK. et al, (2023), bioRxiv

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.

Rodriguez-Meira A. et al, (2023), Nat Genet, 55, 1531 - 1541

A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis

Li R. et al, (2023)

Cooperation between SF3B1 and JAK2 V617F Mutations Accelerates Fibrotic Progression in Myeloproliferative Neoplasms By Enhancing STAT1 Signaling

Sullivan JO. et al, (2023), BLOOD, 142

A tale of two alleles: TP53 and transformation in MPNs.

Brierley C. and Psaila B., (2022), Blood, 139, 3567 - 3568

Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms

Li R. et al, (2022), BLOOD, 140, 1091 - 1092

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