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Researchers at the MRC Weatherall Institute of Molecular Medicine have developed a new platform based on CRISPR/Cas9 technology, to alter the way human cells respond to external signals.

Antanaviciute Group (iCase): The GI Chronicle project: Exploring the effect of age on intestinal epithelial & immune function

Bannard Group: Development of Antibody-Mediated Immunity following Infection and Vaccination (B Cell Immunology)

Chakraverty Group: Identifying novel CD4+ T cell platforms for immunotherapy

Antanaviciute Group: Decrypting human intestinal development

Ogg Group: Discovery of new approaches to treat skin inflammation

Sharma Group: Comparative Analysis of TCR-Mediated Cytotoxicity Using Genome-Wide CRISPR Screens to Identify Host Factors in Natural vs. Vaccine-Induced Immunity

Simmons Group: Engineering Intestinal Mesenchymal Niches to Promote Epithelial Barrier Health Through Life

Nerlov Group: Single Cell Biology and Machine Learning in Blood Development, Cancer and Ageing

Twigg Group: Pathogenic mechanisms in craniofacial malformations

Koohy Group: Decoding the underlying rules of T cell response by AI and Machine-Learning strategies

Koohy Group: Decoding the underlying rules of T cell response by AI and Machine-Learning strategies

Chakraverty Group: Identifying novel CD4+ T cell platforms for immunotherapy

Ogg Group: Discovery of new approaches to treat skin inflammation

Sharma Group: Comparative Analysis of TCR-Mediated Cytotoxicity Using Genome-Wide CRISPR Screens to Identify Host Factors in Natural vs. Vaccine-Induced Immunity

Simmons Group: Engineering Intestinal Mesenchymal Niches to Promote Epithelial Barrier Health Through Life

Antanaviciute Group: Decrypting human intestinal development

MRC WIMM lab projects managed through other Oxford DPhil programmes

The MRC WIMM hosts research groups from various departments in the Medical Sciences Division, in addition to those from the Radcliffe Department of Medicine. Projects advertised here are offered by WIMM supervisors through DPhil programmes other than the RDM DPhil in Medical Sciences.

Kassouf Group: Understanding the principles of gene expression in health and disease

Kassouf Group: Understanding the principles of gene expression in health and disease

Goriely Group: Investigating the role of genetic mosaicism in congenital disease

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