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Found 143 matches for
Sharma Group: Mechanistic T Cell Genomics
Our research team is focused on uncovering the mechanisms that govern T cell signaling, with the goal of precisely engineering immune cells for immunotherapies.
Skin Immunology Group
The aim of the group is to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. We have a particular focus on T cells which recognise inflammatory lipids presented by CD1a. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Dong Group | T cell responses against Viruses & Cancer
Our group focuses on determining the factors which affect T cells both in the control of viral infection and in the development of cancer.
Koohy Group: Machine Learning and Integrative Approaches in Immunology
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.
Simmons Group: Intestinal Immunity in Health and Disease
We define how the immune system functions in the intestine to promote health. We uncover the immune pathogenesis of intestinal diseases such as inflammatory bowel disease to develop better ways to treat these disorders.
Ho Group: Translational Lung Immunology
Immune mechanisms of lung injury, regeneration and fibrosis; identifying new therapeutic targets, and improved treatment for idiopathic pulmonary fibrosis and sarcoidosis.
Bannard Group: B Cell Immunology
We study the cellular and molecular events responsible for shepherding the development of protective antibodies during infection and after immunisation. Our main focus is the germinal centre reaction.
Jackson Group: Lymphatic Trafficking Research Group
We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.
Oxford Centre for Neuroinflammation
We bring together biomedical, analytical and clinical expertise to shed new light on the causes that underpin neurodegenerative diseases.
Davis Group: T-cell Biology
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Drakesmith Group: Iron and Immunity
We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.
Cornall Group: B cell development and immune regulation
Our aims are to understand B cell development and diseases associated with abnormal antibody production. Inadequate or excessive immune responses lead to immunodeficiency or autoimmune and inflammatory diseases, which place a major economic and social burden on world health and the quality of human life. So, we are interested in the normal processes of immune function and how individuals vary due to inherited or acquired differences.