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© 2017 Elsevier Ltd The human immune system is composed of a collection of specialized cells and secreted proteins that allows the identification and removal of an invading pathogen, and in doing so limits host injury or death. This system is composed of innate and adaptive branches. It is important to recognize that although the innate and adaptive branches of the immune system differ fundamentally in their mechanisms of pathogen recognition, neither branch functions in isolation. In this article, we address how the innate and adaptive immune systems sense the presence of a pathogen, how the immune system then coordinates anti-pathogen effector functions to remove the pathogen, and finally how immunological memory functions to better protect its host against subsequent exposure to the same pathogen.

Original publication

DOI

10.1016/j.mpmed.2017.07.003

Type

Journal article

Journal

Medicine (United Kingdom)

Publication Date

01/10/2017

Volume

45

Pages

587 - 596