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A 15 year old boy with sickle cell disease developed intrahepatic cholestasis. A course of exchange transfusion successfully corrected the extreme hyperbilirubinaemia over one year. Upon stopping the exchange transfusion programme the hyperbilirubinaemia relapsed but transfusion was effective when reinstituted.

Original publication

DOI

10.1136/gut.37.1.144

Type

Journal article

Journal

Gut

Publication Date

07/1995

Volume

37

Pages

144 - 147

Keywords

Adolescent, Anemia, Sickle Cell, Cholestasis, Intrahepatic, Chronic Disease, Exchange Transfusion, Whole Blood, Humans, Hyperbilirubinemia, Male, Recurrence