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This month the MRC WIMM hosted the annual Regional Breast Cancer Academic Day, an event that brings together breast cancer teams from across the Thames Valley region. This year’s symposium involved the participation of over 70 attendees, including nurses, clinical trial managers, researchers and doctors.
Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection.
Journal article
Sampaio NG. et al, (2026), Nat Immunol
Gut microbiota restricts intestinal lipid uptake via modulation of bile phosphatidylcholine metabolism in mice.
Journal article
Brunner S. et al, (2026), Nat Microbiol, 11, 2349 - 2364
The Thrombopoietin Receptor S264F Mutant Drives MPN with Marrow Fibrosis Through a Dual Mechanism
Journal article
MEAD A., (2026), HemaSphere
Resolving hematopoietic stem versus progenitor cell potential in the mouse dorsal aorta by differential Runx1 +110 enhancer activity.
Journal article
Anselmi G. et al, (2026), Cell Rep, 45
Nucleophagy as an emerging therapeutic vulnerability in cancer.
Journal article
Tribble S. and Ramadan K., (2026), Autophagy, 1 - 3
The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.
Journal article
Boucher AC. et al, (2026), Leukemia
Identification and masking of artefactual and misleading within-host variants in deep-sequencing SARS-CoV-2 data.
Journal article
Anker K. et al, (2026), Molecular Biology and Evolution (MBE)
Identification of a novel deeply quiescent neural stem cell population in the subventricular zone: a potential source for brain repair.
Journal article
Nath AR. et al, (2026), Cell Discov, 12
Transcriptomic analysis of tissue-resident memory T cells of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention.
Journal article
Wang L. et al, (2026), Nat Commun
The challenge and promise of studying human antigen-specific T cells.
Journal article
Farrar S. et al, (2026), Nat Rev Immunol
Magrolimab Plus Azacitidine Versus Placebo Plus Azacitidine in Patients With Untreated Higher-Risk Myelodysplastic Syndromes: The Phase III ENHANCE Study.
Journal article
Sallman DA. et al, (2026), J Clin Oncol
Immunology of pregnancy and sepsis: shared and specific pathways guiding future precision care.
Journal article
Amarasinghe HE. et al, (2026), EBioMedicine, 130
Forging New Pathways in Oncology: Strategic Insights from the 17th Annual Frontiers in Cancer Science Conference.
Journal article
Huang D. et al, (2026), Cancer Res, 86, 3106 - 3108
CDIN1-Codanin-1 complex defective in congenital dyserythropoietic anaemia type I is an RNA nuclease.
Conference paper
Brolih S. et al, (2026), Nat Commun
CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis.
Journal article
Rampotas A. et al, (2026), Sci Transl Med, 18
VDJ-REMIX: REpertoire Module Identification and eXploration.
Journal article
Amin S. et al, (2026), Bioinformatics, 42
Meta-analysis reveals microbiome signatures for colorectal cancer that are universal across age groups and sequencing methods.
Journal article
Pekel S. et al, (2026), Cell host & microbe, 34, 1462 - 1476.e5
TiO2 Alternative Coatings for Ferric Pyrophosphate Premixes: Stability and Bioaccessibility Relative to Ferrous Fumarate
Journal article
Teichman DL. et al, (2026), Innovative Food Science and Emerging Technologies, 111
TRANSFORM-1 Phase 3 study: Efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.
Journal article
Pemmaraju N. et al, (2026), Blood